So Jason Burns from Nutanix recently published a blog on the Nutanix Next community, which details how to install an F5 BIG-IP on the Nutanix Acropolis Hypervisor. You can read it here.

Jason worked with me, and using my Installing BIG-IP on Nutanix using VMware ESXi article as a starting point he came up with the steps needed to accomplish a similar thing on Nutanix's own Acropolis hypervisor.