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Error Code 10061: Connection refused

I am trying to access a set of servers configured to be load-balanced by F5 through an ISA proxy. I get this error message from the proxy each time I try to access it:

Error Code 10061: Connection refused Background:The server you are attempting to access has refused the connection with the gateway. This usually results from trying to connect to a service that is inactive on the server.

Please, how can I resolve this problem?

Thank you in advance

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USER ACCEPTED ANSWER & F5 ACCEPTED ANSWER

it appears to be an ISA error. are you sure access is allowed via the F5, does the source IP perhaps change and is denied? does the ISA log help you at all?

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Comments on this Answer
Comment made 19-Jan-2015 by Sadorect 390
It is F5 that's refusing connection from the proxy. Clients connect to F5 via the proxy but F5 is refusing the connection. That's the issue. Thank you
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Comment made 19-Jan-2015 by boneyard 5399
im not sure that is the case, the error you mention (Error Code 10061) seems related to ISA not to F5. i can't find a source saying the F5 would report that on itself.
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