I am new to F5 LTM.
How to configre Virtual server
There is a lot of good info where you can understand the workings of the F5 device.
Go to support.f5.com
Lingesh, go ahead and take the free course at # university.f5.com to get the understanding on how we can create virtual server. And answer for your question, YES you can create a route domain for the Public IP subnet you want and you can start using the Public IP as a VIP IP.
If you dont want go for a detail study , or just to create a VIP below is the option :
Login to F5 box --> Click on Local Traffic --> Virtual Server --> Create --> Give all necessary parameters. If you still have questions , feel free to reply. I can help you configuring a Virtual server.