Is there any Document,best practices available on Hardening Guideloines/Security Beseline for F5 Loadbalancer

In the first instance I'd suggest you work you way through this: http://support.f5.com/kb/en-us/solutions/public/13000/000/sol13092.html.

Here's a quick and dirty list of things I think about where the HMS is concerned (includes some of the above) - most of these would apply to any Linux system;

• DDos settings (defaults are generally good) see here: https://f5.com/solutions/architectures/ddos-protection/ddos-exclusive
• Management access and source IP restrictions, idle times, banners etc.
• SSH ciphers for management access
• SSL ciphers for management GUI access
• User roles, admin partitions etc.
• Audit logging
• SNMP community and restrictions
• NTP security
• Local password policy
• Disable root account (perhaps admin too)
• Local and remote logging
• Port Lockdown
• Implement packet filters on the management interface (v11.3 onwards)

And then for LTM;

• Use OneConnect to minimise server impact
• Use Deferred Accept
• Disable Reset on Timeout
• Consider SSL ciphers and settings carefully
• Reduce idle timeouts if necessary
• VLAN Source check
• VLAN keyed connections
• QoS/Rate Limiting/shaping
• Use iRules to protect against basic attacks
• Connection rate limits