Question about accessing virtual server coming from a Cisco ASA webvpn with link translation

I don't really know where to start troubleshooting this issue. We recently migrated our OWA environment behind our F5 LTM's. Everything works fine, with one exception, our Cisco ASA webvpn.

If a user accesses the webvpn and then goes to our OWA environment (through the F5's) they get an internal server error. However, if they go directly to the farm bypassing the F5 then it works fine.

The Cisco ASA's are doing link translation, which is the only different use case scenario to what our typical users are doing. I have the exchange folks digging into their logs, but of course their thought is that if it doesn't work when going through the F5 but does work when going directly to exchange then it's an issue with the F5. B/c we are encrypting all the way through there isn't much I can see in packet captures b/c everything is encrypted.

Thoughts...on where I should even start? I have been digging through dev central, b/c I figured that there is something that causes access from webvpn's with link translation to break...but I haven't found anything.

Thanks in advance!