The F5 AMI's will behave the same as your on-premise LB's so the configuration for vip, monitors, and YES/NO to SNAT should remain the same. I haven't configured FTP in Amazon yet per se, but my more complex on-premise configs migrated seamlessly to AWS. I use Globalscape EFT using their DMZ proxy architecture and it handles most of the complex routing for segregated FTP services, and the BIG-IP is really just LBing the proxies; the proxies do act as the FTP server and then setup a proprietary connection to the "storage" locations behind it.
BIG-IP in AWS does offer a free trial (30 days I think) so you could actually set this up and test it for free. :-)