Yes, lopsided in the answers the GTM gives out for that wideip.
I should have provided more information. The requests are coming from a load generator, which is sending the requests via https (it never changes to http). If we remove the port 443 pool members and add the port 80 pool members in the middle of testing the requests even out between the pool members. In theory the requests should obtain an IP from the GTM and then head straight to the port 443 VSs on the LTMs. Trying to figure out why it even matters what port the GTM pool members are using. Ah ha! The GTM is monitoring the port 80 VSs on the LTM, which should have no traffic/connections. Hmmmm, what does Least Connections do when there are zero connections?