This sounds like it's coming from Qualys and it's complaining about certain HTTP headers like X-Frame-Options, X-XSS-Protection, X-Content-Type-Options, CSP etc headers being missing from the HTTP response. You can add them all via an iRule to tighten the security headers and it's covered in great detail here:
Part 1: https://devcentral.f5.com/articles/tightening-the-security-of-http-traffic-part-1-27511
Part 2: https://devcentral.f5.com/articles/tightening-the-security-of-http-traffic-part-2-27512
Part 3: https://devcentral.f5.com/articles/tightening-the-security-of-http-traffic-part-3-27702