Hi Larry,
When a pool member is marked down, corresponding persistence entries seem to be removed from the persistence table. So when you use the persist command, the request will be load balanced and a new persistence record will be added.
See this post for a recent discussion of the details:
how to use persist lookup command
http://devcentral.f5.com/Default.aspx?tabid=53&aft=55954&afc=1172528
I don't think there is a hard coded limit on the number of persistence table entries that can be added. I think it's dependent on memory available. I'm not exactly clear on how much memory TMM allocates for persistence records or whether TMM will allocate more. Maybe someone can elaborate on this?
Your last sentence was incomplete. Did you have another question?
Aaron