Persistence on HTTPS using iRules

The problem that I see with that is that you are going to be passing traffic over SSL and not decrypting it. When you say the application cannot use SSL offload, well what about passing through the F5, decrypting your packets and then re-encrypting your packets with the same SSL certificate before passing it back on to the server over port 443? I just do not see how you can pull off persistence because you are really limited in the type of Events that you can call on because the traffic is encrypted.