Pool Selection and Persistence using iRule

Yes it's possible to forward traffic to a specific pool based on the HTTP host header. As far as I know it's not possible to persist with a timeout specified in milliseconds. The timeout for persistence should be in seconds. For an iRule like this, it's better to use the switch function. See example below.

when HTTP_REQUEST {
    switch [string tolower [HTTP::host]] {
        "ad.test.xya.com" {
            pool xya_Test--pool
        }
        "bc.test.xya.com" {
            pool xya_Test--pool
        }
        "vf.test.xya.com" {
            pool xya_Test--pool
        }
        "lg.test.xya.com" {
            pool xya_Test--pool
            persist source_addr
        }
        default {
            pool Default_VIP--pool
        }
    }
}