URL Redirect Switch not detecting on host for base domain

I had to remove the ";" after ";, but otherwise your iRule syntax works as expected for me.

You could try using

curl

curl -iv -H "Host: domain.com" http:///

If it works, compare against the output of:

curl -iv http://domain.com/

While your iRule syntax isn't wrong, it could be re-written as:

when HTTP_REQUEST {
    switch [string tolower [HTTP::host]] {
        "domain.com" -
        "www.domain.com" -
        "uat.domain.com" {
            HTTP::respond 301 Location "https://[HTTP::host][HTTP::uri]"
        }
        default {
            pool default_pool
        }
    }
}