Microsoft Exchange 2010, unable to connect through outlook.

I apologize from the start that question is not related to F5 but still I know you Guys helps everyone. I have deployed other vendor load balancers for exchange 2010.

Problem is that the OWA is working fine properly load balanced between two CAS servers.But during configuring outlook and press check names it says that unable to connect to the server. I made the microsoft administrator to use static port for RPC CA.

I have one VS and one pool with 2 CAS servers as members.

My question is that whether RPC protocol requires persistence? if yes which one?