F5 Current Connections

That number is the total of all established clientside connections. These include Real User connections, but also app-to-app connections that are merely routed via F5 in your local network (i.e Forwarding type VS). It's not a good number to refer to when trying to determine the number of Real Users. For that, I would recommend you to request statistics from the application team. It would be virtually impossible to come up with that number by counting connections in F5 because 1 network connection rarely equates to 1 Real User. It can be anywhere from 1 to 20 connections per 1 Real User with typical modern apps.

If you would like to determine the number of current connections for a particular application, you can do that by navigating to

Local Traffic -> Virtual Servers -> Statistics

. In this view, the field "Current" is what you're looking for. Another interesting field "Max" is the all-time peak of current connections since last counter reset or reboot.