AFM and APM conflict ?

Can anybody explain how AFM is configured and shown in VPE ? Does ACLs in AFM and APM for same resources have any conflicting results using the virtual server.

Example "

APM Config: Virtual server : 172.16.1.200 lease pool : 192.168.1.1 - 5 resource : 172.16.15.150, 172.16.15.140

AFM rules: source :any Destination : 172.16.15.150 , 172.16.15.140 port : tcp 80 action : default (Deny)/Accept

Without AFM configuration I am able to have work APM just fine(client gets the ip from the pool and successfully log in into resource). Will there be impact if I configured a deny rule on AFM using policy rule and applied to the virtual server.