Interesting inputs. I've added comments
Take the conf file back up
(bash) cp /config/bigip.conf /config/bigip.conf_backup
Sure, why not.
This will give additional assurance in case you decide to roll back lets say a few days later, not shortly after the change. Naturally, there's another backup file (/config/bigip.conf.bak) which does the exact same thing. At all times, you effectively have an opportunity to roll back a single configuration change regardless if you take a backup or not. However, the bigip.conf.bak file like the main backup file updates itself automatically after changes to configuration are made. This backup file has a very short shelf life. If you consider a change risky, it's never a bad idea to take a hard backup for youself.
Verify the config file
(bash) tmsh load sys config verify
Not a fan.
If there are problems with the configuration file from which you try to load the active configuration, the operation is cancelled automatically and any errors will be reported. Despite F5 recommending this 'verify' flag in various SOL articles, I'd say this command is next to useless and only wastes your time in the long run.